Real Isolates

March 28, 2022 - Real Isolates has formed a subsidiary named Smokenol Day™ to manufacture and sell hemp-derived Smokenol products containing low to no detectable levels of THC.  These 'CBD' products are available on-line and at retail stores under the brand 'Profound Naturals™'.

For wholesale inquiries for Profound Naturals™ hemp-derived (CBD) products please contact sales@Realisolates.com.

Garden Remedies in Massachusetts is the very first licensee of the Smokenol extraction technology. Their innovative product, Sleep+,  is high in cannabinol (CBN). You can pick up Sleep+ capsules at a Garden Remedies dispensary in Melrose, Newton, and Marlborough and at other Massachusetts medical and recreational dispensaries that carry Sleep+.

The Real Isolates companies do not manufacture medical or adult-use cannabis products but do license the patent-pending Smokenol™ extraction method to other companies.  Contact sales@Realisolates.com to discuss licensing for your company.

Real Isolates moves into our new lab space at the Cummings Emerging Tech Center Beverly, MA (!)

Dr. Miyabe Shields, Chief Scientific Officer (CSO) at Real Isolates recently gave a talk at Cannabis Grand Rounds presented by Pivital Edu. Dr. Shields discussed how the endocannabinoid system is involved in the regulation and dysregulation of mental health. These matters are particularly pressing following the COVID19 pandemic, as we’ve seen substantial increases in the diagnosis of anxiety and depressive disorders. 

Real Isolates has developed a commercially viable pyrolytic extraction method to harvest cannabinoids and terpenes from cannabis smoke.  These patent-pending formulations are rich in common and rare cannabinoids (including pyrocannabinoids and pyroterpenes) and enable a new category of oral, topical, and inhaled cannabis therapies. 

Smokenol™ products are made under license from Real Isolates, LLC.  Consumers and product manufacturers may learn more on the Smokenol.com site.  For inquiries about IP licensing please contact Sales@Realisolates.com

Smokenol Sessions is a free cannabis education video resource with content for all backgrounds and abilities about cannabis and the endocannabinoid system.

Videos will range from beginner (no scientific background) to advanced (masters and/or PhD level content) and are created under the direction of Dr. Miyabe Shields, PhD, Chief Scientific Officer of Real Isolates LLC, co-inventor of Smokenol™, endocannabinoid system pharmacology expert, and cannabis patient.

Dr. Miyabe Shields, PHD has their PhD in pharmaceutical sciences and specializes in cannabinoid and endocannabinoid pharmacology.  They will present at the American Chemical Society 2021 Conference in the section “Cannabis Derived Treatments for Specific Medical Conditions: Macromolecular Interactions and Justifications.”  Dr. Shields will be discussing the therapeutic mechanisms of cannabis for mental health disorders. 

Real Isolates LLC files PCT and US Patent application for our novel extraction method of plant and fungus material and novel chemical formulation of cannabinoids.

The PCT application allows Real Isolates to seek protection in most countries in the world. The PCT application and non-provisional US patent application, if granted, have the potential to give 20 years of patent protection for both the method and chemical formulation.