The Future of Natural Extraction is in the Smoke

Real Isolates is pioneering a breakthrough in natural extraction—capturing rare and powerful compounds directly from the smoke of plants and fungi.
real isolates cannabis smoke extraction
A Patented Process

About Real Isolates

We Don’t Make Products—We Make Breakthroughs.

Real Isolates’ patented extraction process captures rare, heat-transformed oils—such as our flagship Smokenol™—from hemp, cannabis, and other botanicals, cleanly, efficiently, and at scale. Our licensable platform powers the next generation of wellness, functional food, and plant-based therapeutics.

We Smoked It for You™

Why Smokenol™

Let’s be honest—smoking isn’t good for you, but over 75% of medical cannabis patients say they prefer the effects of smoking over edibles—and for good reason. Smoking transforms the plant’s chemistry, creating a richer spectrum of active ingredients, including additional cannabinoids that don’t exist in the raw plant. Conventional extraction methods can’t capture them.

Smokenol™ does. Our patented process captures valuable compounds—including cannabinoids, and pyrocannabinoids—created by smoking but missed by standard extraction, without the harmful byproducts of combustion. The result is a clean, scalable ingredient for therapeutic products in topical, oral, inhalable, and other formats.

Smokenol™ – We Smoked It for You™

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What We Do

A New Paradigm for Natural Extraction

We are a science-first company focused on:
  • Licensing Proprietary IP to forward-thinking partners
  • Collaborating with R&D Teams to apply the patented extraction method to other plants and fungi
  • Driving Innovation in Wellness & Cannabis via licensed product integrations
  • Educating the Market about pyrocannabinoids and heat-transformed compounds
Powered by Smokenol Day™

Profound Naturals™

Real Isolates’ subsidiary, Smokenol Day™, brings the benefits of our hemp smoke derived extract to the hemp wellness market.

Profound Naturals™ products feature Smokenol Day™, a hemp-derived version of our solventless extract with low to no detectable THC. These products enable a more complete and fast-acting cannabinoid experience—available online and in select retail stores.

  • Hemp-Derived
  • No Detectable THC
  • Made with Smokenol Day™

Shop Now or learn more about wholesale opportunities.

Our Partners

Who We Work With

IP Licensees: Manufacturers, extractors, and product developers looking to stand out with a differentiated active ingredient.

Researchers & Media: Journalists, academics, and thought leaders interested in next-gen extraction science.

Investors: Partners seeking scalable, defensible biotech IP with broad market potential.

real isolates cannabis smoke extraction
real isolates cannabis smoke extraction

People Love Our Products

Customer Reviews

Let’s Unlock What’s Possible

Whether you’re developing next-gen wellness products or writing the next headline in extraction science, we’d love to connect.