
Real Isolates is pioneering a breakthrough in natural extraction, capturing rare and powerful compounds directly from the smoke of plants and fungi.
We Don’t Make Products. We Make Breakthroughs.
Real Isolates’ patented extraction process captures rare, heat-transformed oils, such as our flagship Smokenol™, from hemp, cannabis, and other botanicals, cleanly, efficiently, and at scale. Our licensable platform powers the next generation of wellness, functional food, and plant-based therapeutics.
Let’s be honest… smoking isn’t good for you, but over 75% of medical cannabis patients say they prefer the effects of smoking over edibles, and for good reason. Smoking transforms the plant’s chemistry, creating a richer spectrum of active ingredients, including additional cannabinoids that don’t exist in the raw plant. Conventional extraction methods can’t capture them.
Smokenol™ does. Our patented process captures valuable compounds, including cannabinoids, and pyrocannabinoids, created by smoking but missed by standard extraction, without the harmful byproducts of combustion. The result is a clean, scalable ingredient for therapeutic products in topical, oral, inhalable, and other formats.
Smokenol™ – We Smoked It for You™


















Real Isolates’ subsidiary, Smokenol Day™, brings the benefits of our hemp smoke derived extract to the hemp wellness market.
Profound Naturals™ products feature Smokenol Day™, a hemp-derived version of our solventless extract with low to no detectable THC. These products enable a more complete and fast-acting cannabinoid experience, available online and in select retail stores.
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IP Licensees: Manufacturers, extractors, and product developers looking to stand out with a differentiated active ingredient.
Researchers & Media: Journalists, academics, and thought leaders interested in next-gen extraction science.
Investors: Partners seeking scalable, defensible biotech IP with broad market potential.
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