Summary:

This computational study investigates how pyrocannabinoids—compounds formed through the combustion of cannabis—interact with major protein targets in the human body. Using molecular docking and in silico modeling, the research identified strong binding affinities between several pyrocannabinoids and receptors like CB1, CB2, and TRPV1. These interactions suggest that combustion products may have therapeutic roles distinct from raw or vaporized cannabinoids.

Key Takeaways:

• Pyrocannabinoids show potential activity at pain- and inflammation-related receptors.
• Findings support combustion as a unique route of cannabinoid activation.
• Highlights the pharmacological value of Real Isolates’ combustion-derived extracts.

Real Isolates Relevance:

This study validates the foundation of Real Isolates’ core technology—extracting and standardizing combustion-activated cannabinoids (pyrocannabinoids). It reinforces the scientific rationale for Real Isolates’ IP and its use in therapeutic applications.